Novel immunosuppressive agent caerulomycin A exerts its effect by depleting cellular iron content
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چکیده
منابع مشابه
Dihydroartemisinin Exerts Its Anticancer Activity through Depleting Cellular Iron via Transferrin Receptor-1
Artemisinin and its main active metabolite dihydroartemisinin, clinically used antimalarial agents with low host toxicity, have recently shown potent anticancer activities in a variety of human cancer models. Although iron mediated oxidative damage is involved, the mechanisms underlying these activities remain unclear. In the current study, we found that dihydroartemisinin caused cellular iron ...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2015
ISSN: 0007-1188
DOI: 10.1111/bph.13051